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Proteins and Peptides

Recombinant Mouse IL-13 Protein

Product Sizes
10 ug
£163.00
RP01596-10UG
20 ug
£223.00
RP01596-20UG
50 ug
£336.00
RP01596-50UG
100 ug
£508.00
RP01596-100UG
500 ug
£1478.00
RP01596-500UG
1000 ug
£2335.00
RP01596-1000UG
About this Product
SKU:
RP01596
Additional Names:
Interleukin-13, IL-13, T-Cell Activation Protein P600, Il13, Il-13,IL13,Interleukin-13, IL-13, T-Cell Activation Protein P600, Il13, Il-13,IL13
Extra Details:
Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6. IL13 initially binds IL-13RA Alpha1 with low affinity and triggers association of IL4R A Alpha , generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13RA Alpha2 with high affinity, which plays a role in a negative feedback system of IL13 signaling. IL13 is an important mediator of allergic inflammation and disease.
Formulation:
Recombinant Mouse IL-13 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser26-Phe131) of mouse IL-13 (Accession #NP_032381.1) fused with and a 6xH
Immunogen:
Ser26-Phe131
Molecular Weight:
15-35 kDa
Physical State:
Lyophilized
Purity:
≥95%
Sequence:
SVSLPLTLKELIEELSNITQDQTPLCNGSMVWSVDLAAGGFCVALDSLTNISNCNAIYRTQRILHGLCNRKAPTTVSSLPDTKIEVAHFITKLLSYTKQLFRHGPF
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins