Recombinant Mouse IL1RL1/ST2 Protein
Product Sizes
10 ug
£133.00
RP01538-10UG
20 ug
£181.00
RP01538-20UG
50 ug
£240.00
RP01538-50UG
100 ug
£353.00
RP01538-100UG
500 ug
£1002.00
RP01538-500UG
1000 ug
£1574.00
RP01538-1000UG
About this Product
- SKU:
- RP01538
- Additional Names:
- DER4 ,FIT-1 ,IL1RL1 ,IL33R ,IL?1?R4 ,ST2 ,ST2L ,ST2V ,T1,IL1RL1
- Extra Details:
- IL-1 receptor-like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.
- Formulation:
- Recombinant Mouse IL1RL1/ST2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser27-Arg332) of mouse IL-1RL1/ST2 (Accession #NP_001020773.1) fused
- Immunogen:
- Ser27-Arg332
- Molecular Weight:
- 50-70 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥95%
- Sequence:
- SKSSWGLENEALIVRCPQRGRSTYPVEWYYSDTNESIPTQKRNRIFVSRDRLKFLPARVEDSGIYACVIRSPNLNKTGYLNVTIHKKPPSCNIPDYLMYSTVRGSDKNFKITCPTIDLYNWTAPVQWFKNCKALQEPRFRAHRSYLFIDNVTHDDEGDYTCQFTHAENGTNYIVTATRSFTVEEKGFSMFPVITNPPYNHTMEVEIGKPASIACSACFGKGSHFLADVLWQINKTVVGNFGEARIQEEEGRNESSSNDMDCLTSVLRITGVTEKDLSLEYDCLALNLHGMIRHTIRLRRKQPIDHR
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:RP01538
