Recombinant Human PTPRC/CD45RA/CD45 Protein
Product Sizes
10 ug
£133.00
RP01529-10UG
20 ug
£181.00
RP01529-20UG
50 ug
£240.00
RP01529-50UG
100 ug
£353.00
RP01529-100UG
500 ug
£1002.00
RP01529-500UG
1000 ug
£1574.00
RP01529-1000UG
About this Product
- SKU:
- RP01529
- Additional Names:
- B220,CD45,CD45R,GP180,L-CA,LCA,LY5,T200,PTPRC, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, receptor-type tyrosine-protein phosphatase C
- Extra Details:
- The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. CD45 is found expression specifically in hemotopietic cells. CD45 consists of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. It serves as an essential regulator of T-cell and B-cell antigen receptor signaling through either direct interaction with components of the antigen receptor complexes or by activating various Src family kinases required for the antigen receptor signaling and it also can suppress JAK kinases.
- Formulation:
- Recombinant Human PTPRC/CD45RA/CD45 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln26-Lys482) of human PTPRC/CD45/CD45RA (Accession #AAD15273.
- Immunogen:
- Gln26-Lys482
- Molecular Weight:
- 100-150 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥95%
- Sequence:
- QSPTPSPTGLTTAKMPSVPLSSDPLPTHTTAFSPASTFERENDFSETTTSLSPDNTSTQVSPDSLDNASAFNTTDAYLNASETTTLSPSGSAVISTTTIATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASVSISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNITYRFQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIFCRSEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSLHAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYHLEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSK
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:RP01529
