Recombinant Mouse YKL-40/CHI3L1 Protein
Product Sizes
10 ug
£133.00
RP01514-10UG
20 ug
£181.00
RP01514-20UG
50 ug
£240.00
RP01514-50UG
100 ug
£353.00
RP01514-100UG
500 ug
£1002.00
RP01514-500UG
1000 ug
£1574.00
RP01514-1000UG
About this Product
- SKU:
- RP01514
- Additional Names:
- CHI3L1,YKL-40,CGP-39,GP-39,ASRT7,CHI3L1
- Extra Details:
- Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.
- Formulation:
- Recombinant Mouse YKL-40/CHI3L1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Tyr30-Ala389) of mouse YKL-40/CHI3L1 (Accession #NP_031721.2) fuse
- Immunogen:
- Tyr30-Ala389
- Molecular Weight:
- 42-48 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥95%
- Sequence:
- YKLVCYFTSWSQYREGVGSFLPDAIQPFLCTHIIYSFANISSDNMLSTWEWNDESNYDKLNKLKTRNTNLKTLLSVGGWKFGEKRFSEIASNTERRTAFVRSVAPFLRSYGFDGLDLAWLYPRLRDKQYFSTLIKELNAEFTKEVQPGREKLLLSAALSAGKVAIDTGYDIAQIAQHLDFINLMTYDFHGVWRQITGHHSPLFQGQKDTRFDRYSNVNYAVQYMIRLGAQASKLLMGIPTFGKSFTLASSENQLGAPISGEGLPGRFTKEAGTLAYYEICDFLKGAEVHRLSNEKVPFATKGNQWVGYEDKESVKNKVGFLKEKKLAGAMVWALDLDDFQGTCQPKEFFPLTNAIKDALA
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:RP01514
