Recombinant Human IL-36R/IL-1Rrp2/IL1RL2 Protein
Product Sizes
10 ug
£133.00
RP01435-10UG
20 ug
£181.00
RP01435-20UG
50 ug
£240.00
RP01435-50UG
100 ug
£353.00
RP01435-100UG
500 ug
£1240.00
RP01435-500UG
1000 ug
£1954.00
RP01435-1000UG
About this Product
- SKU:
- RP01435
- Additional Names:
- IL1RL2,IL-1Rrp2,IL-36R,IL1R-rp2,IL1RRP2,IL36R
- Extra Details:
- IL1RL2 (Interleukin 1 Receptor-Like 2, also known as IL-36R) is a Protein Coding gene. The protein encoded by this gene is a member of the interleukin 1 receptor family. This gene and four other interleukin 1 receptor family genes form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. The IL36 receptor is an important mediator molecule in the inflammatory response. Animal data suggest that IL1RL2 is involved in mucosal healing. Therapeutic intervention of IL-36R signaling offers an innovative treatment paradigm for targeting epithelial cell-mediated inflammatory diseases such as the life-threatening psoriasis variant called generalized pustular psoriasis (GPP). Diseases associated with IL1RL2 include Familial Cold Autoinflammatory Syndrome 2 and Geographic Tongue.
- Formulation:
- Recombinant Human IL-36R/IL-1Rrp2/IL1RL2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp20-Arg335) of human IL-1 Rrp2/IL-1 R6 (Accession #NP_0
- Immunogen:
- Asp20-Arg335
- Molecular Weight:
- 55-65 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥95%
- Sequence:
- DGCKDIFMKNEILSASQPFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDESKRIREGVETHVSFREHNLYTVNITFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFR
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:RP01435
