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Proteins and Peptides

Recombinant Mouse Noggin/NOG Protein

Product Sizes
10 ug
£127.00
RP01308-10UG
50 ug
£240.00
RP01308-50UG
100 ug
£336.00
RP01308-100UG
About this Product
SKU:
RP01308
Additional Names:
noggin,NOG
Extra Details:
Recombinant Mouse Noggin/NOG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln28-Cys232) of mouse Noggin (Accession #NP_032737.1) fused with an 6xHis tag at the C-terminus.
Formulation:
Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4.
Immunogen:
Gln28-Cys232
Molecular Weight:
24.75 kDa
Physical State:
Lyophilized
Purity:
≥95%
Sequence:
QHYLHIRPAPSDNLPLVDLIEHPDPIFDPKEKDLNETLLRSLLGGHYDPGFMATSPPEDRPGGGGGPAGGAEDLAELDQLLRQRPSGAMPSEIKGLEFSEGLAQGKKQRLSKKLRRKLQMWLWSQTFCPVLYAWNDLGSRFWPRYVKVGSCFSKRSCSVPEGMVCKPSKSVHLTVLRWRCQRRGGQRCGWIPIQYPIISECKCSC
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Recombinant Mouse Noggin/NOG Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
Immobilized recombinant Human BMP4 at 0.5 ug/mL (100 uL/well) can bind Noggin with a linear range of 4-29 ng/mL.
Immobilized recombinant Human Noggin at 1 ug/mL (100 uL/well) can bind Noggin Rabbit pAb with a linear range of 1-4.95 ng/mL.
Recombinant human NOG inhibits BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 3.5-14 ng/mL in the presence of 50 ng/mL of Recombinant Human BMP-4.