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Proteins and Peptides

Recombinant Human TNF-alpha Protein

Product Sizes
20 ug
£133.00
RP00993-20UG
50 ug
£163.00
RP00993-50UG
100 ug
£240.00
RP00993-100UG
About this Product
SKU:
RP00993
Additional Names:
TNF, DIF, TNF-alpha, TNFA, TNFSF2, TNLG1F, tumor necrosis factor,TNF-A Alpha,DIF,TNF-alpha,TNFA,TNFSF2,TNLG1F,TNF alpha
Extra Details:
Recombinant Human TNF-alpha Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val 77 - Leu 233 ) of human TNF-alpha (Accession #NP_000585.2) fused with a 6xHis tag at the C-terminus.
Formulation:
Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Immunogen:
Val77-Leu233
Molecular Weight:
18.19 kDa
Physical State:
Lyophilized
Purity:
≥95%
Sequence:
VRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Recombinant Human TNF-alpha Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
Recombinant Human TNF-alpha induces cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 0.90-3.60 ng/mL, corresponding to a specific activity of 2.78x105~1.11x106 units/mg.
At concentrations ranging from 0.01 to 5 ng/mL, M5 factor (RP03505 IL1A,RP00212 IL17A,RP01616 IL22,RP00993 TNFA Alpha,RP00054 OSM)promotes the proliferation of HaCaT cells.