Recombinant Human LGR5 / GPR49 protein
Product Sizes
10 ug
£145.00
RP00730-10UG
20 ug
£193.00
RP00730-20UG
50 ug
£264.00
RP00730-50UG
100 ug
£395.00
RP00730-100UG
500 ug
£1157.00
RP00730-500UG
1000 ug
£1812.00
RP00730-1000UG
About this Product
- SKU:
- RP00730
- Additional Names:
- LGR5, GPR49, GPR67,Leucine-rich repeat-containing G-protein coupled receptor 5
- Extra Details:
- LGR5 (also known as GPR49) is a seven-transmembrane protein of the class A Rhodopsin-like family of GPCRs. LGR5 and LGR4 bind the R-spondins with high affinity and mediate the potentiation of Wnt/B Beta-catenin signaling by enhancing Wnt-induced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3.
- Formulation:
- Recombinant Human LGR5 / GPR49 protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly 22 - Arg 561) of Human LGR5 / GPR49(Accession #NM_003667.3) fus
- Immunogen:
- Gly22-Arg561
- Molecular Weight:
- 60-80 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥90%
- Sequence:
- GSSPRSGVLLRGCPTHCHCEPDGRMLLRVDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKLTGNHALQSLISSENFPELKVIEMPYAYQCCAFGVCENAYKISNQWNKGDNSSMDDLHKKDAGMFQAQDERDLEDFLLDFEEDLKALHSVQCSPSPGPFKPCEHLLDGWLIR
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:RP00730
