Recombinant Human Serpin E1/PAI-1 Protein
Product Sizes
10 ug
£193.00
RP00532-10UG
20 ug
£258.00
RP00532-20UG
50 ug
£383.00
RP00532-50UG
100 ug
£586.00
RP00532-100UG
500 ug
£1716.00
RP00532-500UG
1000 ug
£2716.00
RP00532-1000UG
About this Product
- SKU:
- RP00532
- Additional Names:
- PAI,PAI-1,PAI1,PLANH1,SERPINE1
- Extra Details:
- Serpins are a group of proteins with similar structures that were first identified as a set of proteins able toinhibit proteases. They are the largest and most diverse family of serine protease inhibitors which are involvedin a number of fundamental biological processes such as blood coagulation, complement activation,fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.Serpin E1 is a secreted protein which belongs to the Serpin family. Serpin E1 acts as 'bait' for tissueplasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major controlpoint in the regulation of fibrinolysis. Defects in SERPINE1 are characterized by abnormal bleeding due toSerpin E1 defect in the plasma. High concentrations of Serpin E1 have been associated with thrombophiliawhich is an autosomal dominant disorder in which affected individuals are prone to develop seriousspontaneous thrombosis.
- Formulation:
- Recombinant Human Serpin E1/PAI-1 Protein is produced by Human cells expression system. The target protein is expressed with sequence (Val24-Pro402) of human Serpin E1 (Accession #P05121) fused with a
- Immunogen:
- Val24-Pro402
- Molecular Weight:
- 45-60 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥95%
- Sequence:
- VHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:RP00532
