Recombinant Human CTLA-4/CD152 Protein
Product Sizes
100 ug
£240.00
RP00503-100UG
500 ug
£645.00
RP00503-500UG
1000 ug
£1193.00
RP00503-1000UG
About this Product
- SKU:
- RP00503
- Additional Names:
- ALPS5|CD152|CELIAC3|CTLA4|GRD4|GSE|ICOS|IDDM12
- Extra Details:
- CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation - a phenomenon which is particularly notable in cancers. It acts as an "off" switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.
- Formulation:
- Recombinant Human CTLA-4/CD152 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys36-Asp161) of Human CTLA-4/CD152 (Accession #P16410-1) fused wit
- Immunogen:
- Lys36-Asp161
- Molecular Weight:
- 50-55 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥ 95 % as determined by SDS-PAGE;≥ 95 %
- Sequence:
- KAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSD
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:RP00503
