Biotinylated Recombinant Human PTPRC/CD45R0/CD45 Protein
Product Sizes
100 ug
£657.00
RP00395B-100UG
500 ug
£1954.00
RP00395B-500UG
1000 ug
£3858.00
RP00395B-1000UG
About this Product
- SKU:
- RP00395B
- Additional Names:
- B220|CD45|CD45R|EC 3.1.3.48|GP180|L-CA|LCA|LY5|PTPRC|T200
- Conjugate:
- Biotin
- Extra Details:
- PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts.
- Formulation:
- Biotinylated Recombinant Human PTPRC/CD45R0/CD45 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln26--Lys416) of Human PTPRC/CD45R0/CD45 (Access
- Immunogen:
- Gln26--Lys416
- Molecular Weight:
- 80-110 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥ 95 % as determined by SDS-PAGE;≥ 95 %
- Sequence:
- QSPTPSPTDAYLNASETTTLSPSGSAVISTTTIATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASVSISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNITYRFQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIFCRSEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSLHAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYHLEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSK
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:RP00395B
