Biotinylated Recombinant Human TNFRSF1B/TNF-R2/CD120b Protein (Primary Amine Labeling)
Product Sizes
100 ug
£657.00
RP00364B-100UG
500 ug
£1954.00
RP00364B-500UG
1000 ug
£3382.00
RP00364B-1000UG
About this Product
- SKU:
- RP00364B
- Additional Names:
- CD120b|Etanercept|p75TBPII|p75TNFR|TBPII|TNF RII|TNF-R2|TNF-R75|TNFBR|TNFR1B|TNFR2|TNFR80|TNFRSF1B
- Conjugate:
- Biotin
- Extra Details:
- Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
- Formulation:
- Biotinylated Recombinant Human TNFRSF1B/TNF-R2/CD120b Protein (Primary Amine Labeling) is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu23-Asp257) of Hu
- Immunogen:
- Leu23-Asp257
- Molecular Weight:
- 40-60 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥ 95 % as determined by SDS-PAGE;≥ 95 %
- Sequence:
- LPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGD
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Manufacturer's Data Sheet:RP00364B
