Recombinant Human CEACAM1/CD66a Protein
Product Sizes
10 ug
£127.00
RP00294-10UG
20 ug
£175.00
RP00294-20UG
50 ug
£240.00
RP00294-50UG
100 ug
£336.00
RP00294-100UG
500 ug
£1002.00
RP00294-500UG
1000 ug
£1574.00
RP00294-1000UG
About this Product
- SKU:
- RP00294
- Additional Names:
- BGP, BGP1, BGPI,CEACAM1,BGP1,BGPI
- Extra Details:
- The secreted recombinant human CEACAM1 comprises 405amino acids with a molecular weight of 45 kDa. The apparent molecular mass of recombinant human CEACAM1 is about 65-85 kDa in SDS-PAGE under reducing conditions due to glycosylation.Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is also known as Biliary glycoprotein 1 (BGP1), CD66a belonging to the immunoglobulin superfamily or CEA family. CEACAM1 /CD66a contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells and was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia.The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.
- Formulation:
- Recombinant Human CEACAM1/CD66a Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln35-Gly428) of human CEACAM1 (Accession #NP_001703.2) fused with
- Immunogen:
- Gln35-Gly428
- Molecular Weight:
- 60-80 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥95%
- Sequence:
- QLTTESMPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPG
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:RP00294
