Recombinant Human Trk-C/NTRK3 Protein
Product Sizes
20 ug
£181.00
RP00288-20UG
50 ug
£240.00
RP00288-50UG
100 ug
£353.00
RP00288-100UG
500 ug
£1002.00
RP00288-500UG
1000 ug
£1574.00
RP00288-1000UG
About this Product
- SKU:
- RP00288
- Additional Names:
- NTRK3,GP145-TrkC,TRKC,gp145(trkC)
- Extra Details:
- NT-3 growth factor receptor also known as neurotrophic tyrosine kinase receptor type 3 or TrkC tyrosine kinase or Trk-C receptor, is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in TrkC encoding gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
- Formulation:
- Recombinant Human Trk-C/NTRK3 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Cys32-Asp428) of human TrkC/NTRK3 (Accession #NP_001012338.1) fused with a
- Immunogen:
- Cys32-Asp428
- Molecular Weight:
- 110-130 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥95%
- Sequence:
- CPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEED
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:RP00288
