Recombinant Human SIRP-alpha/CD172a Protein
Product Sizes
10 ug
£127.00
RP00285-10UG
20 ug
£175.00
RP00285-20UG
50 ug
£240.00
RP00285-50UG
100 ug
£336.00
RP00285-100UG
500 ug
£1002.00
RP00285-500UG
1000 ug
£1574.00
RP00285-1000UG
About this Product
- SKU:
- RP00285
- Additional Names:
- BIT, CD172A, MFR, MYD-1, P84, PTPNS1, SHPS1, SIRP,SIRPA,CD172A,MFR,MYD-1,P84,PTPNS1,SHPS1,SIRP
- Extra Details:
- The protein is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein.
- Formulation:
- Recombinant Human SIRP-alpha/CD172a Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Glu31-Arg370) of human SIRP alpha/CD172a (Accession #NP_542970) fuse
- Immunogen:
- Glu31-Arg370
- Molecular Weight:
- 40-70 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥95%
- Sequence:
- EEELQVIQPDKSVLVAAGETATLRCTATSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNTAAENTGSNER
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:RP00285
