Recombinant Human CD5L Protein
Product Sizes
10 ug
£133.00
RP00198-10UG
20 ug
£181.00
RP00198-20UG
50 ug
£240.00
RP00198-50UG
500 ug
£1002.00
RP00198-500UG
1000 ug
£1574.00
RP00198-1000UG
About this Product
- SKU:
- RP00198
- Additional Names:
- CD5L,AIM,API6,CT-2,PRO229,SP-ALPHA,Spalpha,hAIM
- Extra Details:
- CD5L (CD5 antigen-like), also known as Sp alpha and AIM, is a 50 kDa secreted glycoprotein that belongs to the SRCR (scavenger receptor cysteine rich) group B family of proteins. CD5L is up-regulated in macrophages at inflammatory sites. It sustains inflammatory reactions by both increasing the phagocytic capacity of macrophages and impeding the apoptosis of local macrophages, NK cells, and T cells. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. In the thymic cortex, CD5L protects cortical CD4+CD8+thymocytes from apoptosis. CD5L circulates in the serum in complex with IgM.
- Formulation:
- Recombinant Human CD5L Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser20-Gly347) of human CD5L/API6 (Accession #NP_005885.1) fused with a 6xHi
- Immunogen:
- Ser20-Gly347
- Molecular Weight:
- 40-45 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥90%
- Sequence:
- SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQEEVYDCSHDEDAGASCENPESSFSPVPEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICSG
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:RP00198
