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Proteins and Peptides

Recombinant Human Siglec-3/CD33 Protein

Product Sizes
10 ug
£133.00
RP00159-10UG
20 ug
£181.00
RP00159-20UG
50 ug
£240.00
RP00159-50UG
100 ug
£353.00
RP00159-100UG
500 ug
£1002.00
RP00159-500UG
1000 ug
£1574.00
RP00159-1000UG
About this Product
SKU:
RP00159
Additional Names:
CD33, SIGLEC-3, SIGLEC3, p67, CD33 molecule,SIGLEC-3,SIGLEC3,p67
Extra Details:
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This Single-pass type I membrane protein contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD33/Siglec-3 induces apoptosis in acute myeloid leukemia (in vitro). CD33/Siglec-3 can function as a sialic acid-dependent cell adhesion molecule and that binding can be modulated by endogenous sialoglycoconjugates when CD33 is expressed in a plasma membrane.
Formulation:
Recombinant Human Siglec-3/CD33 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Asp18-His259) of human CD33/Siglec-3 (Accession #NP_001763.3) fused with
Immunogen:
Asp18-His259
Molecular Weight:
Approximately 75 kDa
Physical State:
Lyophilized
Purity:
≥95%
Sequence:
DPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVH
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins