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Proteins and Peptides

Recombinant Human Serpin C1/Antithrombin-III Protein

Product Sizes
20 ug
£258.00
RP00140-20UG
50 ug
£383.00
RP00140-50UG
100 ug
£586.00
RP00140-100UG
500 ug
£1716.00
RP00140-500UG
1000 ug
£2716.00
RP00140-1000UG
About this Product
SKU:
RP00140
Additional Names:
AT3, AT3D, ATIII, THPH7,SERPINC1,AT3D,ATIII,THPH7
Extra Details:
The protein is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
Formulation:
Recombinant Human SerpinC1/AntithrombinIII/ATIII Protein is produced by HEK293 expression system. The target protein is expressed with sequence (His33-Lys464) of human SerpinC1/AntithrombinIII/ATIII (
Immunogen:
His33-Lys464
Molecular Weight:
50-70 kDa
Physical State:
Lyophilized
Purity:
≥95%
Sequence:
HGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins