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Proteins and Peptides

Recombinant Human DDR2/CD167b Protein

Product Sizes
20 ug
£181.00
RP00115-20UG
50 ug
£240.00
RP00115-50UG
100 ug
£353.00
RP00115-100UG
500 ug
£1002.00
RP00115-500UG
1000 ug
£1574.00
RP00115-1000UG
About this Product
SKU:
RP00115
Additional Names:
DDR2,MIG20a,NTRKR3,TKT,TYRO10, NTRKR3, TKT, TYRO10
Extra Details:
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.
Formulation:
Recombinant Human DDR2/CD167b Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln24-Arg399) of human DDR2 Kinase/CD167b Kinase/CD167b (Accession #
Immunogen:
Gln24-Arg399
Molecular Weight:
55-65 kDa
Physical State:
Lyophilized
Purity:
≥95%
Sequence:
QVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTR
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes