Recombinant Human GDNFR-alpha-1/GFRA1 Protein
Product Sizes
20 ug
£133.00
RP00102-20UG
50 ug
£163.00
RP00102-50UG
500 ug
£645.00
RP00102-500UG
1000 ug
£1002.00
RP00102-1000UG
About this Product
- SKU:
- RP00102
- Additional Names:
- GFRA1,GDNFR,GDNFRA,GFR-ALPHA-1,RET1L,RETL1,TRNR1
- Extra Details:
- This protein is a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
- Formulation:
- Recombinant Human GDNFR-alpha-1/GFRA1 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala19-Lys429) of human GFRA1/GFRA Alpha1/GDNFRA (Accession #NP_665
- Immunogen:
- Ala19-Lys429
- Molecular Weight:
- 100 kDa
- Physical State:
- Lyophilized
- Purity:
- 85%
- Sequence:
- AEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSPYEPVNSRLSDIFRVVPFISVEHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSSSLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPVQTTTATTTTALRVKNKPLGPAGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCISNGNYEKEGLGASSHITTK
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:RP00102
