Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

Recombinant Human Oncostatin-M/OSM Protein

Product Sizes
10 ug
£145.00
RP00054-10UG
20 ug
£193.00
RP00054-20UG
50 ug
£264.00
RP00054-50UG
100 ug
£395.00
RP00054-100UG
500 ug
£1157.00
RP00054-500UG
1000 ug
£1812.00
RP00054-1000UG
About this Product
SKU:
RP00054
Additional Names:
OSM, oncostatin-M
Extra Details:
This protein is a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family. The preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells.
Formulation:
Recombinant Human Oncostatin-M/OSM Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ala26-Arg221) of human Oncostatin-M/OSM (Accession #NP_065391.1).
Immunogen:
Ala26-Arg221
Molecular Weight:
20-25 kDa
Physical State:
Lyophilized
Purity:
≥95%
Sequence:
AAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYIRIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGCVLHRLADLEQRLPKAQDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTPASDAFQRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRR
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Recombinant Human Oncostatin-M/OSM Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue. Recombinant Human Oncostatin-M/OSM Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue. At concentrations ranging from 0.01 to 5 ng/mL, M5 factor (RP03505 IL1A,RP00212 IL17A,RP01616 IL22,RP00993 TNFA Alpha,RP00054 OSM)promotes the proliferation of HaCaT cells. Measured in a cell proliferation assay using TF-1 Human erythroleukemic cells. The ED50 for this effect is 0.76-3.04 ng/mL, corresponding to a specific activity of 3.9x105~1.31x106 units/mg. Measured in a cell proliferation assay using TF-1 Human erythroleukemic cells. The ED50 for this effect is 0.76-3.04 ng/mL, corresponding to a specific activity of 3.9x105~1.31x106 units/mg. Recombinant Human OSM promotes the proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.8-3.2 ng/mL, corresponding to a specific activity of 3.12x105-1.25x106units/mg.