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Proteins and Peptides

Recombinant Human MANF Protein

Product Sizes
10 ug
£127.00
RP00005-10UG
50 ug
£223.00
RP00005-50UG
100 ug
£336.00
RP00005-100UG
500 ug
£907.00
RP00005-500UG
1000 ug
£1478.00
RP00005-1000UG
About this Product
SKU:
RP00005
Additional Names:
MANF,ARMET,ARP
Extra Details:
The protein is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this protein increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in Normal tissues and are thus no longer thought to be tumor-related.
Formulation:
Recombinant Human MANF Protein is produced by E. coli expression system. The target protein is expressed with sequence (Leu25-Leu182) of human MANF (Accession #NP_006001.4).
Immunogen:
Leu25-Leu182
Molecular Weight:
Approximately 18 kDa
Physical State:
Lyophilized
Purity:
≥95%
Sequence:
LRPGDCEVCISYLGRFYQDLKDRDVTFSPATIENELIKFCREARGKENRLCYYIGATDDAATKIINEVSKPLAHHIPVEKICEKLKKKDSQICELKYDKQIDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPKAASARTDL
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins