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Antibodies

Rabbit anti-Human Pro-Collagen I/COL1A1 monoclonal antibody

Product Sizes
100 ug
£438.00
RMK0616-100UG
200 ug
£647.00
RMK0616-200UG
500 ug
£1503.00
RMK0616-500UG
1000 ug
£2741.00
RMK0616-1000UG
About this Product
SKU:
RMK0616
Additional Names:
CAFYD|EDSARTH1|EDSC|OI1|OI2|OI3|OI4
Application:
ELISA
Clonality:
Monoclonal
Extra Details:
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Formulation:
Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.3.
Immunogen:
Recombinant Human Pro-Collagen I/COL1A1 protein
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C
Supplier:
ABclonal Technology
Type:
Antibody: Monoclonal Antibody