Rabbit anti- Human TRAIL/TNFSF10 monoclonal antibody
Product Sizes
100 ug
£438.00
RMK0438-100UG
200 ug
£599.00
RMK0438-200UG
500 ug
£1503.00
RMK0438-500UG
1000 ug
£2741.00
RMK0438-1000UG
About this Product
- SKU:
- RMK0438
- Additional Names:
- Apo-2L|APO2L|CD253|TANCR|TL2|TNLG6A|TRAIL
- Application:
- ELISA
- Clonality:
- Monoclonal
- Extra Details:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Formulation:
- Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human TRAIL/TNFSF10
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:RMK0438
