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Antibodies

Rabbit anti-Human GM-CSF monoclonal antibody

Product Sizes
100 ug
£438.00
RMK0249-100UG
200 ug
£599.00
RMK0249-200UG
500 ug
£1503.00
RMK0249-500UG
1000 ug
£2741.00
RMK0249-1000UG
About this Product
SKU:
RMK0249
Additional Names:
CSF|GMCSF
Application:
Detection/Quantitation
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis.
Formulation:
Supplied as a 0.2um filtered solution in PBS with 0.05% Proclin300, PH 7.4.
Immunogen:
Recombinant Human GM-CSF Protein
Isotype:
IgG
Purification:
Affinity Purified
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C
Supplier:
ABclonal Technology
Type:
Antibody: Monoclonal Antibody