Rabbit anti-Human TNF RII/TNFRSF1B monoclonal antibody
Product Sizes
100 ug
£438.00
RMK0236-100UG
200 ug
£599.00
RMK0236-200UG
500 ug
£1503.00
RMK0236-500UG
1000 ug
£2741.00
RMK0236-1000UG
About this Product
- SKU:
- RMK0236
- Additional Names:
- CD120b|p75|p75TNFR|TBPII|TNF-R-II|TNF-R75|TNFBR|TNFR1B|TNFR2|TNFR80
- Application:
- Detection/Quantitation
- Clonality:
- Monoclonal
- Extra Details:
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
- Formulation:
- Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
- Immunogen:
- Recombinant human TNF RII/TNFRSF1B Protein
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:RMK0236
