Rabbit anti-Human B Beta-Amyloid 1-42 monoclonal antibody
Product Sizes
100 ug
£438.00
RMK0217-100UG
200 ug
£599.00
RMK0217-200UG
500 ug
£1503.00
RMK0217-500UG
1000 ug
£2741.00
RMK0217-1000UG
About this Product
- SKU:
- RMK0217
- Additional Names:
- AAA|ABETA|ABPP|AD1|alpha-sAPP|APPI|CTFgamma|CVAP|PN-II|PN2|preA4
- Clonality:
- Monoclonal
- Extra Details:
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Formulation:
- Supplied as a 0.2um filtered solution in PBS with 0.05% Proclin300, PH 7.4.
- Immunogen:
- A synthetic peptide corresponding to a sequence within amino acids 591-690 of human B Beta-Amyloid (NP_000475.1).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:RMK0217
