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Antibodies

Rabbit anti-Human TRAIL R3/ TNFRSF10C monoclonal antibody

Product Sizes
100 ug
£438.00
RMK0174-100UG
200 ug
£599.00
RMK0174-200UG
1000 ug
£2741.00
RMK0174-1000UG
About this Product
SKU:
RMK0174
Additional Names:
CD263|DCR1|DCR1-TNFR|LIT|TRAIL-R3|TRAILR3|TRID
Application:
ELISA
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
Formulation:
Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
Immunogen:
Recombinant Human TRAIL R3/ TNFRSF10C
Isotype:
IgG
Purification:
Affinity Purified
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C
Supplier:
ABclonal Technology
Type:
Antibody: Monoclonal Antibody