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Antibodies

Rabbit anti-Human LILRB1 monoclonal antibody (DET)

Product Sizes
100 ug
£438.00
RM17934-100UG
500 ug
£1503.00
RM17934-500UG
1000 ug
£2521.00
RM17934-1000UG
About this Product
SKU:
RM17934
Additional Names:
CD85J|ILT-2|ILT2|LIR-1|LIR1|MIR-7|MIR7|PIR-B|PIRB
Application:
ELISA
Clonality:
Monoclonal
Extra Details:
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Formulation:
Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
Immunogen:
Recombinant Human LILRB1
Isotype:
IgG
Purification:
Affinity Purified
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Monoclonal Antibody