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Antibodies

Rabbit anti-Human CRP monoclonal antibody

Product Sizes
100 ug
£438.00
RM17827-100UG
1000 ug
£2741.00
RM17827-1000UG
About this Product
SKU:
RM17827
Additional Names:
PTX1
Application:
ELISA
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection.
Formulation:
Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, PH 7.4.
Host:
Rabbit
Immunogen:
Recombinant human CRP
Isotype:
IgG
Purification:
Affinity Purified
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C
Supplier:
ABclonal Technology
Type:
Antibody: Monoclonal Antibody