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Antibodies

Rabbit anti-Human IL-5 monoclonal antibody (DET)

Product Sizes
100 ug
£438.00
RM17738-100UG
1000 ug
£2741.00
RM17738-1000UG
About this Product
SKU:
RM17738
Additional Names:
EDF|IL-5|TRF
Application:
CLIA, Detection/Quantitation, ELISA
Clonality:
Monoclonal
Extra Details:
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Formulation:
Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
Host:
Rabbit
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-134 of human IL-5 (NP_000870.1).
Isotype:
IgG
Purification:
Affinity Purified
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C
Supplier:
ABclonal Technology
Type:
Antibody: Monoclonal Antibody