Rabbit anti-Human TNF-alpha(CAP)
Product Sizes
100 ug
£438.00
RM17698-100UG
200 ug
£599.00
RM17698-200UG
500 ug
£1503.00
RM17698-500UG
1000 ug
£2741.00
RM17698-1000UG
About this Product
- SKU:
- RM17698
- Additional Names:
- DIF|TNF-alpha|TNFA|TNFSF2|TNLG1F
- Application:
- Detection/Quantitation
- Extra Details:
- This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
- Formulation:
- Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
- Immunogen:
- E. coli-derived human TNF-alpha protein Val77-Leu233 Accession #P01375
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- ABclonal Technology
- Type:
- Antibody
- Manufacturer's Data Sheet:RM17698
