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Antibodies

SR-B2/LIMPII Rabbit monoclonal antibody

Product Sizes
5 ul
£ POA
A9185-5UL
20 ul
£163.00
A9185-20UL
100 ul
£342.00
A9185-100UL
500 ul
£1532.00
A9185-500UL
1000 ul
£2704.00
A9185-1000UL
About this Product
SKU:
A9185
Additional Names:
AMRF|CD36L2|EPM4|HLGP85|LGP85|LIMP-2|LIMPII|SR-B2/LIMPII|SR-BII
Application:
ELISA, IHC-Paraffin, Western Blot
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Formulation:
Unmodified
Host:
Rabbit
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Isotype:
IgG
Molecular Weight:
75kDa
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Sequence:
MGRCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRELRNKANI
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:A9185
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