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Antibodies

Pyruvate carboxylase (PC) Rabbit monoclonal antibody

Product Sizes
5 ul
£ POA
A8980-5UL
20 ul
£163.00
A8980-20UL
100 ul
£342.00
A8980-100UL
500 ul
£1532.00
A8980-500UL
1000 ul
£2704.00
A8980-1000UL
About this Product
SKU:
A8980
Additional Names:
PC|PCB|Pyruvate carboxylase (PC)
Application:
ELISA, Western Blot
Clonality:
Monoclonal
Extra Details:
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
Formulation:
Unmodified
Host:
Rabbit
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Isotype:
IgG
Molecular Weight:
130kDa
Purification:
Affinity Purified
Reactivities:
Mouse, Rat
Sequence:
MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIP
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:A8980
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