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Antibodies

ING3 Rabbit polyclonal antibody

Product Sizes
20 ul
£152.00
A5832-20UL
100 ul
£336.00
A5832-100UL
500 ul
£1258.00
A5832-500UL
1000 ul
£2228.00
A5832-1000UL
About this Product
SKU:
A5832
Additional Names:
Eaf4|ING2|ING3|MEAF4|p47ING3
Application:
ELISA, Western Blot
Clonality:
Polyclonal
Extra Details:
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
Formulation:
Unmodified
Host:
Rabbit
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Isotype:
IgG
Molecular Weight:
50kda
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Sequence:
MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADEKVQLANQIYDLQHF
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Polyclonal Antibody
  • Manufacturer's Data Sheet:A5832