COMT Rabbit monoclonal antibody
Product Sizes
5 ul
£ POA
A4435-5UL
20 ul
£164.00
A4435-20UL
100 ul
£342.00
A4435-100UL
500 ul
£1532.00
A4435-500UL
1000 ul
£2704.00
A4435-1000UL
About this Product
- SKU:
- A4435
- Additional Names:
- COMT|HEL-S-98n
- Application:
- ELISA, Western Blot
- Clonality:
- Monoclonal
- Extra Details:
- Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
- Formulation:
- Unmodified
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Isotype:
- IgG
- Molecular Weight:
- 25kDa/28kDa
- Purification:
- Affinity Purified
- Reactivities:
- Human, Rat
- Sequence:
- MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIV
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:A4435
