PE Rabbit anti-Human Perforin monoclonal antibody
Product Sizes
10 tests
£ POA
A28870-10TESTS
100 tests
£288.00
A28870-100TESTS
200 tests
£479.00
A28870-200TESTS
500 tests
£1056.00
A28870-500TESTS
About this Product
- SKU:
- A28870
- Additional Names:
- HPLH2|P1|PFP
- Application:
- Flow Cytometry
- Clonality:
- Monoclonal
- Extra Details:
- Perforin is a pore-forming protein, and its transmembrane channel formation mechanism is similar to that of C9. It has been proven that perforin is homologous to C9. Studies have shown that perforin is expressed only in cytotoxic cell lines and not in helper T lymphocytes or other tested tumor cells. It is well known that perforin is a key effector molecule in T cell and natural killer cell-mediated cytotoxicity. Defects in the perforin gene lead to familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and fatal autosomal recessive genetic disease in early childhood. Alternative splicing leads to multiple transcriptional variants of perforin.
- Formulation:
- Unmodified
- Host:
- Rabbit
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:A28870
