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Antibodies

Caspase-1 Rabbit monoclonal antibody

Product Sizes
5 ul
£ POA
A28849-5UL
20 ul
£164.00
A28849-20UL
100 ul
£342.00
A28849-100UL
500 ul
£1371.00
A28849-500UL
1000 ul
£2544.00
A28849-1000UL
About this Product
SKU:
A28849
Additional Names:
ICE|Il1bc
Application:
ELISA, Western Blot
Clonality:
Monoclonal
Extra Details:
Enables cysteine-type endopeptidase activity. Involved in several processes, including AIM2 inflammasome complex assembly; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of interleukin-1 beta production. Acts upstream of or within several processes, including membrane hyperpolarization; mitochondrial depolarization; and positive regulation of cytokine production. Located in extracellular region. Part of IPAF inflammasome complex. Is active in cytosol. Is expressed in several structures, including forelimb mesenchyme; knee joint; oocyte; small intestine; and telencephalon. Orthologous to human CASP1 (caspase 1).
Formulation:
Unmodified
Host:
Rabbit
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Isotype:
IgG
Molecular Weight:
22-35 kDa (cleaved)/48 kDa (pro)
Purification:
Affinity Purified
Reactivities:
Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:A28849
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