FITC Rabbit anti-Human MPO monoclonal antibody
Product Sizes
10 tests
£ POA
A28807-10TESTS
100 tests
£259.00
A28807-100TESTS
200 tests
£419.00
A28807-200TESTS
500 tests
£925.00
A28807-500TESTS
About this Product
- SKU:
- A28807
- Application:
- Flow Cytometry
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Extra Details:
- The MPO gene encodes myeloperoxidase, a lysosomal heme protein located in the azurophilic granules of polymorphonuclear (PMN) leukocytes and monocytes. In response to stimulation, MPO is activated to a transient intermediate with potent antimicrobial oxidizing capacity (PMID: 17650507). The mRNA is translated into a single 90 kDa protein that exhibits enzymatic activity and undergoes proteolytic maturation into a 59 kDa heavy chain and a 13.5 kDa light chain; these subunits then dimerize to form the mature tetramer, with mature MPO being an heterotetramer composed of two identical heavy chains and two identical light chains (PMID: 12773517). The 24 kDa material has a profile identical to that of the 13.5 kDa subunit, representing the dimer of the 13.5 kDa subunit (PMID: 3008892). Deficiency of MPO is the cause of myeloperoxidase deficiency (MPOD). It has three isoforms generated by alternative splicing. This antibody is specific for MPO virus.
- Formulation:
- Unmodified
- Host:
- Rabbit
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:A28807
