APC Rabbit anti-Human CD49d monoclonal antibody
Product Sizes
10 tests
£ POA
A28806-10TESTS
100 tests
£259.00
A28806-100TESTS
200 tests
£431.00
A28806-200TESTS
500 tests
£925.00
A28806-500TESTS
About this Product
- SKU:
- A28806
- Additional Names:
- CD49D|IA4
- Application:
- Flow Cytometry
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD49d is a 150 kD A Alpha integrin chain, also known as A Alpha4 integrin or VLA-4A Alpha chain. It forms heterodimers with integrin B Beta1 (A Alpha4B Beta1, VLA-4) or B Beta7 (A Alpha4B Beta7). CD49d is widely expressed on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells and some non-hematopoietic cells, but is not expressed on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. A Alpha4B Beta7 is the receptor for VCAM-1 and MAdCAM-1. CD49d is involved in the transport of monocytes to endothelial inflammatory sites and plays a role in cell-cell interactions and cell adhesion to the extracellular matrix. CD49d is involved in lymphocyte migration, T cell activation and hematopoietic stem cell differentiation. CD49d is a marker for the isolation and purification of pure Treg cell populations because it is absent on Foxp3+ cells.
- Formulation:
- Unmodified
- Host:
- Rabbit
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:A28806
