PerCP/Cyanine5.5 Rabbit anti-Human/Monkey CD86 monoclonal antibody
Product Sizes
10 tests
£ POA
A28689-10TESTS
100 tests
£324.00
A28689-100TESTS
2 x 100 tests
£544.00
A28689-2X100TESTS
5 x 100 tests
£1204.00
A28689-5X100TESTS
About this Product
- SKU:
- A28689
- Additional Names:
- B7-2|B7.2|B70|BU63|CD28LG2|CD86 v6|FUN-1|LAB72
- Application:
- Flow Cytometry
- Clonality:
- Monoclonal
- Conjugate:
- PerCP-Cyanine 5.5
- Extra Details:
- CD86 is an 80 kDa member of the immunoglobulin superfamily, also known as B7-2, B70, and Ly-58. It is expressed on activated B cells and T cells, monocytes/macrophages, dendritic cells, and astrocytes. Together with CD80, CD86 serves as a ligand for both CD28 and CD152 (CTLA-4). During immune responses, CD86 is generally expressed earlier than CD80. CD86 has also been shown to participate in immunoglobulin class switching and to trigger NK cell-mediated cytotoxicity. Upon binding to CD28, CD86 transduces co-stimulatory signals that promote T cell activation, proliferation, and cytokine production. Conversely, engagement of CD86 with CD152 (CTLA-4) delivers inhibitory signals to T cells.
- Formulation:
- Unmodified
- Host:
- Rabbit
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Isotype:
- IgG
- Molecular Weight:
- 38kda
- Purification:
- Affinity Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:A28689
