PE Rabbit anti-Monkey CD22 monoclonal antibody
Product Sizes
10 tests
£ POA
A28610-10TESTS
100 tests
£229.00
A28610-100TESTS
2 x 100 tests
£371.00
A28610-2X100TESTS
5 x 100 tests
£812.00
A28610-5X100TESTS
About this Product
- SKU:
- A28610
- Additional Names:
- SIGLEC-2|SIGLEC2
- Application:
- Flow Cytometry
- Clonality:
- Monoclonal
- Extra Details:
- CD22 is a 130 kDa type I transmembrane glycoprotein, also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesin subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature and activated B cells, but is absent on plasma cells. It is part of the B-cell receptor (BCR) complex and associates with signaling molecules such as SHP-1, Syk, Lck, Lyn, and phospholipase CG Gamma1. The primary function of CD22 is believed to be the limitation of antigen receptor signaling by modulating the threshold for B-cell activation. Studies have shown that CD22 can bind to CD45RO and CD75, although the identity of its natural ligand(s) remains a subject of debate.
- Formulation:
- Unmodified
- Host:
- Rabbit
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Isotype:
- IgG
- Molecular Weight:
- 95 kDa
- Purification:
- Affinity Purified
- Reactivities:
- Non-human Primate
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:A28610
