APC Rabbit anti-Human/Monkey TCR G Gamma/D Delta monoclonal antibody
Product Sizes
10 tests
£ POA
A28555-10TESTS
100 tests
£496.00
A28555-100TESTS
2 x 100 tests
£835.00
A28555-2X100TESTS
About this Product
- SKU:
- A28555
- Additional Names:
- TCRD|TCRDV1|TCRG|TRD@|TRG@
- Application:
- Flow Cytometry
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- The G GammaD Delta T-cell receptor (TCR) is a heterodimer composed of G Gamma and D Delta chains, expressed on the T-cell surface and involved in antigen recognition. The engagement of the G GammaD Delta TCR with antigen triggers the phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) within the CD3 chains. Unlike A AlphaB Beta T cells, human G GammaD Delta T cells recognize and kill transformed cells in a manner unrestricted by human leukocyte antigen (HLA) presentation. G GammaD Delta T lymphocytes primarily develop in the thymus, where their defining receptor is generated through RAG-mediated recombination of a relatively limited repertoire of variable (V), diversity (D), and joining (J) gene segments. In addition to the T-cell receptor, G GammaD Delta T cells often express activating natural killer (NK) receptors, which bind to stress-induced surface molecules frequently expressed on malignant cells.
- Formulation:
- Unmodified
- Host:
- Rabbit
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:A28555
