ABflo[R] 450 Rat anti-Mouse CD16/CD32 monoclonal antibody
Product Sizes
5 ug
£ POA
A28535-5UG
50 ug
£240.00
A28535-50UG
100 ug
£383.00
A28535-100UG
About this Product
- SKU:
- A28535
- Additional Names:
- CD16|CD32|F630109E10Rik|Fc[g]RII|Fcgr2|Fcgr2a|FcgRII|Fcr-2|Fcr-3|fcRII|Ly-17|Ly-m20|LyM-1
- Application:
- Flow Cytometry
- Clonality:
- Monoclonal
- Conjugate:
- ABflo™ 450
- Extra Details:
- CD16 is a 50-65 kDa cell surface molecule that exists in two isoforms: a transmembrane form expressed by natural killer (NK) cells, and a glycosylphosphatidylinositol (GPI)-anchored form expressed by granulocytes. It serves as a low-affinity receptor for IgG (FcG GammaRIII) and is a critical mediator of antibody-dependent cellular cytotoxicity (ADCC) by NK cells. CD32 (Fcgr2) is a 40 kD transmembrane glycoprotein, member of the immunoglobulin superfamily. The extracellular region of CD32 consists of two Ig C-type domains that binds the Fc region from monomeric IgG with low affinity, but binds immune complexes efficiently. CD32 can mediate phagocytosis of immune complexes and modulate cell activation. CD32 is expressed by Macrophages, neutrophils, mast cells and B cells.
- Formulation:
- Unmodified
- Host:
- Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Isotype:
- IgG2b, kappa
- Molecular Weight:
- 31kDa/36kDa
- Purification:
- Affinity Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:A28535
