PE Rabbit anti-Human VEGFR-3/FLT-4 monoclonal antibody
Product Sizes
10 tests
£ POA
A28354-10TESTS
100 tests
£294.00
A28354-100TESTS
200 tests
£497.00
A28354-200TESTS
500 tests
£1098.00
A28354-500TESTS
About this Product
- SKU:
- A28354
- Additional Names:
- CHTD7|FLT-4|FLT41|LMPH1A|LMPHM1|PCL|VEGFR-3|VEGFR3
- Application:
- Flow Cytometry
- Clonality:
- Monoclonal
- Extra Details:
- Vascular Endothelial Growth Factor Receptor 3 (VEGFR3) is a 195 kDa transmembrane receptor tyrosine kinase. The VEGF receptor features seven extracellular immunoglobulin-like (Ig) domains, a single transmembrane domain, and a conserved intracellular tyrosine kinase domain. In adults, VEGFR3 expression is primarily restricted to lymphatic endothelial cells and is known to govern lymphangiogenesis. The binding of VEGF-C or VEGF-D to VEGFR3 induces trans-phosphorylation of tyrosine residues within its intracellular domain. This phosphorylation event facilitates the recruitment of downstream signaling molecules, ultimately leading to the activation of the ERK1/2 and Akt signaling cascades.
- Formulation:
- Unmodified
- Host:
- Rabbit
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Isotype:
- IgG
- Molecular Weight:
- 153 kDa
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Sequence:
- YSMTPPTLNITEESHVIDTGDSLSISCRGQHPLEWAWPGAQEAPATGDKDSEDTGVVRDCEGTDARPYCKVLLLHEVHANDTGSYVCYYKYIKARIEGTTAASSYVFVRDFEQPFINKPDTLLVNRKDAMWVPCLVSIPGLNVTLRSQSSVLWPDGQEVVWDDRRGMLVSTPLLHDALYLQCETTWGDQDFLSNPFLVHITGNELYDIQLLPRKSLELLVGEKLVLNCTVWAEFNSGVTFDWDYPGKQAERGKWVPERRSQQTHTELSSILTIHNVSQHDLGSYVCKANNGIQRFRESTEVIVHENPFISVEWLKGPILEATAGDELVKLPVKLAAYPPPEFQWYKDGKALSGRHSPHALVLKEVTEASTGTYTLALWNSAAGLRRNISLELVVNVPPQIHEKEASSPSIYSRHSRQALTCTAYGVPLPLSIQWHWRPWTPCKMFAQRSLRRRQQQDLMPQCRDWRAVTTQDAVNPIESLDTWTEFVEGKNKTVSKLVIQNANVSAMYKCVVSNKVGQDERLIYFYVTTIPDGFTIESKPSEELLEGQPVLLSCQADSYKYEHLRWYRLNLSTLHDAHGNPLLLDCKNVHLFATPLAASLEEVAPGARHATLSLSIPRVAPEHEGHYVCEVQDRRSHDKHCHKKYLSVQALEAPRLTQNLTDLLVNVSDSLEMQCLVAGAHAPSIVWYKDERLLEEKSGVDLADSNQKLSIQRVREEDAGRYLCSVCNAKGCVNSSASVAVEGSEDKGSMEI
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:A28354
