PE Rabbit anti-Mouse CD70 monoclonal antibody
Product Sizes
2.5 ug
£ POA
A28353-2.5UG
50 ug
£146.00
A28353-50UG
100 ug
£211.00
A28353-100UG
About this Product
- SKU:
- A28353
- Additional Names:
- Cd27l|CD27LG|Tnfsf7|Tnlg8a
- Application:
- Flow Cytometry
- Clonality:
- Monoclonal
- Extra Details:
- CD70 is a type II transmembrane glycoprotein and a member of the tumor necrosis factor ligand superfamily (TNFSF), also known as CD27L and TNFSF7. It is constitutively expressed on medullary thymic epithelial cells. Its expression can be induced on activated lymphocytes (B cells, T cells, and NK cells) and dendritic cells. CD70 serves as the ligand for CD27, a co-stimulatory receptor that plays a critical role in T cell activation and proliferation. Overexpression of CD70 has been reported in various malignancies, such as renal cell carcinoma, glioblastoma, and non-small cell lung carcinoma, and it is being actively pursued as a therapeutic target.
- Formulation:
- Unmodified
- Host:
- Rabbit
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Isotype:
- IgG
- Molecular Weight:
- 22 kda
- Purification:
- Affinity Purified
- Reactivities:
- Mouse
- Sequence:
- QQQRLLEHPEPHTAELQLNLTVPRKDPTLRWGAGPALGRSFTHGPELEEGHLRIHQDGLYRLHIQVTLANCSSPGSTLQHRATLAVGICSPAAHGISLLRGRFGQDCTVALQRLTYLVHGDVLCTNLTLPLLPSRNADETFFGVQWICP
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:A28353
