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Antibodies

Cleaved-Caspase 3 p12 Rabbit monoclonal antibody

Product Sizes
5 ul
£ POA
A28349-5UL
20 ul
£164.00
A28349-20UL
100 ul
£342.00
A28349-100UL
500 ul
£1455.00
A28349-500UL
1000 ul
£2704.00
A28349-1000UL
About this Product
SKU:
A28349
Additional Names:
CPP32|CPP32B|SCA-1
Application:
ELISA, Western Blot
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
Formulation:
Unmodified
Host:
Rabbit
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Isotype:
IgG
Molecular Weight:
12 kDa
Purification:
Affinity Purified
Reactivities:
Human
Sequence:
GIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLT
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:A28349
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