Biotin Rabbit anti-Mouse CD45 monoclonal antibody
Product Sizes
10 ug
£ POA
A28220-10UG
50 ug
£98.00
A28220-50UG
100 ug
£122.00
A28220-100UG
5 x 100 ug
£229.00
A28220-5X100UG
About this Product
- SKU:
- A28220
- Additional Names:
- B220|Cd45|CD45R|L-CA|loc|Ly-5|Lyt-4|T200
- Application:
- Flow Cytometry
- Clonality:
- Monoclonal
- Conjugate:
- Biotin
- Extra Details:
- CD45 is a 180-240 kD glycoprotein, also known as the leukocyte common antigen (LCA), T200, or Ly-5. As a member of the protein tyrosine phosphatase (PTP) family, it is expressed on all hematopoietic cells except mature erythrocytes and platelets. Different isoforms of CD45 are generated through the alternative splicing of exons 4, 5, and 6, which encode the A, B, and C determinant regions, respectively. CD45 plays a critical role in the signal transduction of both the T-cell receptor (TCR) and B-cell receptor (BCR). These isoforms exhibit high specificity for the cell's activation and maturation status, as well as the cell type. Key ligands for CD45 include galectin-1, CD2, CD3, TCR, CD4, CD22, and Thy-1.
- Formulation:
- Unmodified
- Host:
- Rabbit
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Isotype:
- IgG
- Molecular Weight:
- 130 kDa/140 kDa/144 kDa
- Purification:
- Affinity Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:A28220
