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Antibodies

ABflo[R] 450 Rabbit anti-Human/Monkey HLA-DR monoclonal antibody

Product Sizes
10 tests
£ POA
A26274-10TESTS
100 tests
£306.00
A26274-100TESTS
200 tests
£485.00
A26274-200TESTS
500 tests
£860.00
A26274-500TESTS
About this Product
SKU:
A26274
Additional Names:
HLA-DRA1
Application:
Flow Cytometry
Clonality:
Monoclonal
Conjugate:
ABflo™ 450
Extra Details:
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. This molecule is expressed on the surface of various antigen presenting cells such as B lymphocytes, dendritic cells, and monocytes/macrophages, and plays a central role in the immune system and response by presenting peptides derived from extracellular proteins, in particular, pathogen-derived peptides to T cells. The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
Formulation:
Unmodified
Host:
Rabbit
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Isotype:
IgG
Molecular Weight:
29kDa
Purification:
Affinity Purified
Reactivities:
Human, Non-human Primate
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:A26274
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