Chicken IL12B Rabbit polyclonal antibody
Product Sizes
5 ul
£ POA
A25100-5UL
20 ul
£164.00
A25100-20UL
100 ul
£342.00
A25100-100UL
500 ul
£1532.00
A25100-500UL
1000 ul
£2704.00
A25100-1000UL
About this Product
- SKU:
- A25100
- Additional Names:
- IL-12B|IL-12p40
- Application:
- ELISA, Western Blot
- Clonality:
- Polyclonal
- Extra Details:
- Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
- Formulation:
- Unmodified
- Host:
- Rabbit
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Isotype:
- IgG
- Molecular Weight:
- 45kDa
- Purification:
- Affinity Purified
- Reactivities:
- Avian
- Sequence:
- QWKLRENVYVIESEWNDETPAKKVKLTCDTSDEALPVYWKKGTELKGTGKTLTTEVKEFPDAGNYTCLSAKTHEIISYSFFLITKVDSNGQMIRSILKSYKEPSKTFLKCEAKNYSGIFTCSWMTENESPSVKFTIRSLKGSQGDVTCSSPVARTDKSVTEYTAQCQKENYCPFAEEHQPTEMFLEVIDEVEYENYTSSFFIRDIIKPDPPQCQYASTNGTVTWTYPKTWSTPKSYFPLTFRVKVESTKKYKSKVYDADEQSIQIPKTGPKDKISVQARDRYYNSSWSEWSTLCR
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:A25100
